• Conus ascends with development
    • Normal conus terminates at L1-L2 (adult/by 2 mo of birth)
    • L3 at 30 wks
  • Conus is 'low-lying' if tip is below lower border of L2 vertebral body at birth (lower if premature)
  • Stretch-induced dysfunction/injury of caudal spinal cord, caused by attachments of the filum terminale
  • Secondary to myelomeningocele, lipomeningocele, caudal regression/sacral agenesis, etc
  • Bladder dysfunction varies: both lower motor neuron (low contractility) and suprasacral (detrusor overactivity, DSD)
    • Atonic bladder, poor compliance, DESD, ...
    • Urodynamics before and after surgery
  • Progressive motor and sensory dysfunction, gait abnormalities/stumbling
  • Bladder dysfunction
  • Back pain
  • Scoliosis, foot/equinovarus deformities
  • Repair before ***7 years of age?
  • Generally around 4-5 mo
author: last edited: Oct. 31, 2020, 8:21 p.m. | pk: 167 | unpublished