Definition

• Fever: T > 38.3C (101F) x 1, or T > 38.0 (100.4) for > 1 hr
• Fever of unknown origin (FUO): T > 38.3 for > 3 wks without identified source despite intensive eval/testing
• FUO may be nosocomial, HIV, immune deficient
• Neutropenic fever: fever with ANC >= 500 cells/mm3
• Gram negative (E. coli, Klebsiella, Pseudomonas)
• Likely GI flora infection mediated by mucositis/GI side effects of chemo
• Gram positive (staph, enterococcus, viridans strep, strep pneumo)
• Fungal (aspergillus, candida)
• 
• IDSA guidelines - cite

Ddx

• Infxn
• Malignancy
• COnnective tissue disease
• Drugs
• Misc. 

'5 W's of post-op fever'